First thing's first. This is a real, honest-to-goodness review of a piece of hardware I bought. Razer didn't send me a freebie, and I'm not just saying this based on the pictures I've seen of it. I've owned a Razer Naga for a week now, and it's been the best week of my WoW existence (at least in terms of interface).
I've tried a LOT of different kinds of control tools for playing WoW. I took a Nostromo n52 for a spin that lasted a few days (it was pretty cool, but I couldn't get it to consistently go forward - backward - left - right using the thumbpad, I kept going diagonally and there was no tactile feedback, which was a dealbreaker). I've been using a logitech mx-518 (and a third-party mouse driver because Logitech stupidly doesn't have a mac driver for this one mouse), which I also really like. I mapped the six extra mouse buttons on the mx-518 (forward, back, page up, page down, scroll-wheel-click, and the random extra button) to game commands, giving me six buttons I can press with my hands on the mouse. Useful for /cast [target=mouseover] macros, especially for healers. But I'm ditching the 518 for a Naga, and the Naga even has a mac driver.
The basics of the Naga are straightforward - it's a decently ergonomic (right handed only, alas) mouse with some fancy-shmancy infrared laser (so you can blind yourself without noticing, since it's invisible) and a neat blue glow. It is a wired mouse, which I prefer - I still get noticeable lag no matter what kind of wireless mouse I use. It's got a scroll wheel (but no tilt-wheel which I again applaud, I detest tilt-wheel mice) and a forward-back button that is actually kind of hard to press (my one complaint is that I can't hit the back button with any finger in my normal hand configuration).
What's special about the naga? It has 12 more buttons.
Twelve frakkin' buttons. It's like they took your entire numberpad and taped it to the side of the mouse. It's EXACTLY like that.
This means that you can play the game using your left hand for movement and some buttons, and keep your right hand on the mouse at all times, for speedy turning, easy targeting, and so on. It means I don't need to have a keybind for /startattack, because I can just right-click on people now.
After a week of use, I can say that the keypad is precisely right. The mouse comes with some sticky rubber "trainers", little nubs you can put on some of your buttons. I put one on 5 and one on 11. I can very easily use 1-3 and 4-6 without thinking about it, that's where I put all my combat maneuvers on my characters (that's not a change from where I put stuff when I used a regular keyboard, even). 7-9 are a little harder to get to, but they're not too bad. 10-12 *are* something of a challenge to press, I have to consciously think about pressing those buttons. Then again, they're buttons I don't press all that often anyway (curse of elements, evasion, etc), so maybe if I had to use them a lot, I'd get better at it.
At $80 for the mouse, it's a little on the pricey end, but that's about what you'd spend for a fancy mouse anyway (a mx 518 will set you back $40, for example).
It's totally worth getting. Give it a week and acclimate to it, and you'll never need to take your hands off the mouse ever again. I'd even suggest it to Phil - just because you use a laptop doesn't mean you can't mouse also. Although I'm not sure I'd want to do anything requiring precision whilst treadmilling.